Publications

Featured Article:

Single-cell multiplexed cytokine profiling of CD19 CAR-T cells reveals a diverse landscape of polyfunctional antigenspecific response
Qiong Xue, Emily Bettini, Patrick Paczkowski, Colin Ng, Alaina Kaiser, Timothy McConnell, Olja Kodrasi, Máire F. Quigley, James Heath, Rong Fan, Sean Mackay, Mark E. Dudley, Sadik H. Kassim and Jing Zhou
BioMed Central, Journal for ImmunoTherapy of Cancer, 2017.

——————–

 

Leukopak
Effector function of CTLs is increased by irradiated colorectal tumor cells that modulate OX‑40L and 4‑1BBL and is reversed following dual blockade
Anita Kumari and Charlie Garnett‑Benson*
BMC Research Notes. 2016; 9:92.
This article is summarized on HemaCare’s blog

 

Mononuclear Cells
CD40-Mediated NF-κB Activation in B Cells Is Increased in Multiple Sclerosis and Modulated by Therapeutics
Ding Chen, Sara J. Ireland, Gina Remington, Enrique Alvarez, Michael K. Racke, Benjamin Greenberg, Elliot M. Frohman, Nancy L. Monson
Journal of Immunology (December 1, 2016), Volume 197, Number 11, Pages 4257-4265.

 

B cells from relapsing remitting multiple sclerosis patients support neuro-antigen-specific Th17 responses
Sara J. Ireland, Alyssa A. Guzman, Elliot M. Frohman, Nancy L. Monson
Journal of Neuroimmunology 291 (2016) 46-53.
This article is summarized on HemaCare’s blog

 

STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1
Juan Fu, David B. Kanne, Meredith Leong, Laura Hix Glickman, Sarah M. McWhirter, Edward Lemmens, Ken Mechette, Justin J. Leong, Peter Lauer, Weiqun Liu, Kelsey E. Sivick, Qi Zeng, Kevin C. Soares, Lei Zheng, Daniel A. Portnoy, Joshua J. Woodward, Drew M. Pardoll, Thomas W. Dubensky Jr., and Young Kim
Science Translational Medicine; Volume 7, Issue 283, Pages 283ra52, 2015 April 15.
This article is summarized on HemaCare’s blog

 

Human esophageal myofibroblasts secrete pro-inflammatory cytokines in response to acid and toll-like receptor-4 ligands
Matthew Gargus, Chao Niu, John Vallone, Jana Binkley, Deborah C. Rubin, Anisa Shaker
American Journal of Physiology. 2015 April 16.
This article is summarized on HemaCare’s blog

 

Precision Cancer Immunotherapy: Optimizing Dendritic Cell-based Strategies to Induce Tumor Antigen-specific T-cell Responses Against Individual Patient Tumors.
Osada, Takuya; Nagaoka, Koji; Takahara, Masashi; Yang, Xiao Yi; Liu, Cong-Xiao; Guo, Hongtao; Roy Choudhury, Kingshuk; Hobeika, Amy; Hartman, Zachary; Morse, Michael A.; Lyerly, H. Kim
Journal of Immunotherapy. Volume 38, Issue 4, Pages 155–164, May 2015.
This article is summarized on HemaCare’s blog

 

A Subset of CD8αβ+ Invariant NKT Cells in a Humanized Mouse Model.
Xiangshu Wen, Seil Kim, Ran Xiong, Michelle Li, Agnieszka Lawrenczyk, Xue Huang, Si-Yi Chen, Ping Rao, Gurdyal S. Besra, Paolo Dellabona, Giulia Casorati, Steven A. Porcelli, Omid Akbari, Mark A. Exley, and Weiming Yuan
Journal of Immunology. 2015 August; 195:1459-1469.

 

The Effect of Glatiramer Acetate Therapy on Functional Properties of B Cells From Patients With Relapsing-Remitting Multiple Sclerosis
Sara J. Ireland, BA; Alyssa A. Guzman, BS; Dina E. O’Brien, BS; Samuel Hughes; Benjamin Greenberg, MD; Angela Flores, MD; Donna Graves, MD; Gina Remington, BSN, RN; Elliot M. Frohman, MD, PhD; Laurie S. Davis, PhD; Nancy L. Monson, PhD
JAMA Neurology. 2014 September 29
This article is summarized on HemaCare’s blog

 

Identification of novel human leukocyte antigen-A*0201-restricted, cytotoxic T lymphocyte epitopes on CD133 for cancer stem cell immunotherapy.
Jianfei Ji, Valeria A. Judkowski, Gentao Liu, Hongqiang Wang, Alcinette Bunying, Zhenhua Li, Minlin Xu, James Bender, Clemencia Pinilla and John S. Yu
Stem Cells Translational Medicine. 2014 March; 3(3):356-64.
This article is summarized on HemaCare’s blog

 

Nucleotide Insertions and Deletions Complement Point Mutations to Massively Expand the Diversity Created by Somatic Hypermutation of Antibodies.
Peter M. Bowers, Petra Verdino, Zhengyuan Wang, Jean da Silva Correia, Mark Chhoa, Griffin Macondray, Minjee Do, Tamlyn Y. Neben, Robert A. Horlick, Robyn L. Stanfield, Ian A. Wilson, and David J. King
The Journal of Biological Chemistry. 2014 November; 289:33557-33567.
This article is summarized on HemaCare’s blog

 

Reduction of total IgE by targeted coengagement of IgE B-cell receptor and FcγRIIb with Fc-engineered antibody
Seung Y. Chu, PhD,* Holly M. Horton, PhD,* Erik Pong, MS, Irene W. L. Leung, PhD, Hsing Chen, MS, Duc-Hanh Nguyen, BS, Cristina Bautista, BS, Umesh S. Muchhal, PhD, Matthew J. Bernett, PhD, Gregory L. Moore, PhD, David E. Szymkowski, PhD, and John R. Desjarlais, PhD
The Journal of Allergy and Clinical Immunology; Volume 129, Issue 4, Pages 1102-1115, April 2012
This article is summarized on HemaCare’s blog

 

A novel bispecific antibody format enables simultaneous bivalent and monovalent co-engagement of distinct target antigens
Gregory L. Moore*, Cristina Bautista, Erik Pong, Duc-Hanh T. Nguyen, Jonathan Jacinto, Araz Eivazi, Umesh S. Muchhal, Sher Karki, Seung Y. Chu, and Greg A. Lazar
mAbs; 3(6): 546–557; November/December 2011.
This article is summarized on HemaCare’s blog

 

Turning T cells on: epigenetically enhanced expression of effector T-cell costimulatory molecules on irradiated human tumor cells
Anita Kumari, Ercan Cacan, Susanna F Greer and Charlie Garnett-Benson*
Journal for ImmunoTherapy of Cancer 2013, 1:17.
This article is summarized on HemaCare’s blog

 

A Quantitative Polymerase Chain Reaction Test to Enumerate Leukocytes in Allograft Tissue and the Implications for Donor Eligibility Testing
Cari E. Podzemny, Matthew D. Brenton, Scott A. Brubaker, Russell C. Marians
Cells Tissues Organs; Volume 198, Number 3:221-226.
This article is summarized on HemaCare’s blog

 

CD4 T Cells
MCPIP1 restricts HIV infection and is rapidly degraded in activated CD4+ T cells
Shufeng Liu, Chao Qiu, Ruidong Miao, Jianhua Zhou, Aram Lee, Baoming Liu, Sandra N. Lester, Weihui Fu, Lingyan Zhu, Linxia Zhang, Jianqing Xu, Daping Fan, Kui Li, Mingui Fu, and Tianyi Wang
PNAS 2013 110 (47) 19083-19088
This article is summarized on HemaCare’s blog

 

CD19 B Cells
Opportunistic DNA Recombination With Epstein-Barr Virus at Sites of Control Region Rearrangements Mediating JC Virus Neurovirulence
Margaret J. Wortman, Patric S. Lundberg, Ayuna V. Dagdanova, Pranav Venkataraman, Dianne C. Daniel and Edward M. Johnson
The Journal of Infectious Disease, May 2016; 213: 1436 – 1443.
This article is summarized on HemaCare’s blog

 

Macrophages
Suppression of IGF binding protein-3 by palmitate promotes hepatic inflammatory responses
Hae-Ki Min, Hitoshi Maruyama, Byoung Kuk Jang, Masahiko Shimada, Faridoddin Mirshahi, Shunlin Ren, Youngman Oh, Puneet Puri, Arun J. Sanyal
The FASEB Journal (December 2016), Volume 30, Number 12, Pages 4071-4082.

 

Dual Transcriptome Profiling of Leishmania-Infected Human Macrophages Reveals Distinct Reprogramming Signatures
Maria Cecilia Fernandes, Laura A. L. Dillon, Ashton Trey Belew, Hector Corrada Bravo, David M. Mosser, Najib M. El-Sayed
mBio; 10 May 2016; vol. 7, no. 3, e00027-16.
This article is summarized on HemaCare’s blog

 

Unprocessed Bone Marrow
Characterization of the Cellular Output of a Point-of-Care Device and the Implications for Addressing Critical Limb Ischemia
Woodell-May, Jennifer E., Tan, Matthew L., King, William J., Swift, Matthew J., Welch, Zachary R., Murphy, Michael P., McKale, James M.
BioResearch Open Access. November 2015, 4(1): 417-424. 
This article is summarized on HemaCare’s blog

 

Whole Blood
A Novel Technology for Multiplex Gene Expression Analysis Directly from Whole Blood Samples Stabilized at Ambient Temperature Using an RNA-Stabilizing Buffer
Chang Hee Kim, Majid Abedi, Yenbou Liu, Sree Panuganti, Francisco Flores, Kevin R. Shah, Hannah Catterall, Krishna S. Morampudi, Robert Terbrueggen
Journal of Molecular Diagnostics; Volume 17, Issue 2, Pages 118–127, March 2015
This article is summarized on HemaCare’s blog

 

Circulating Tumor Cells: Clinically Relevant Molecular Access Based on a Novel CTC Flow Cell
Jessamine P. Winer-Jones*, Behrad Vahidi, Norma Arquilevich, Cong Fang, Samuel Ferguson, Darren Harkins, Cory Hill, Erich Klem, Paul C. Pagano, Chrissy Peasley, Juan Romero, Robert Shartle, Robert C. Vasko, William M. Strauss, Paul W. Dempsey
PLoS ONE 9(1): e86717.
This article is summarized on HemaCare’s blog

 

Four-part leukocyte differential count based on sheathless microflow cytometer and fluorescent dye assay
Wendian Shi, Luke Guo, Harvey Kasdan, and Yu-Chong Tai*
Lab Chip, 2013, 13, 1257.
This article is summarized on HemaCare’s blog

 

Platelets
The Effects of Platelet-rich Plasma on Cell Proliferation and Adipogenic Potential of Adipose-derived Stem Cells.
Liao HT, James IB, Marra K, Rubin JP
Tissue Engineering Part A. 2015 Sep 29
This article is summarized on HemaCare’s blog

 

Plasma
Optimized Library Prep for Cell-Free DNA from Human Plasma
Jan Risinger, Josh Kinman, Marianna Goldrick
http://www.biooscientific.com
This article is summarized on HemaCare’s blog

 

Serum
Evaluation of a New Recombinant Antigen-Based Virotech Treponema Pallidum Screen ELISA for Diagnosis of Syphilis
Clemens Busse, Mojdeh Heidary Navid, Andreas Strubel, Paul Schnitzler
Clinical Laboratory. 2013;59(5-6):523-9.
This article is summarized on HemaCare’s blog

 

HemaCare
Human-derived raw materials: Controlled, consistent collections enable successful manufacturing of cell-based regenerative medicine products.
Thomas Ramos, Wenshi Wang, PhD, Jacob Okhovat, Gaytha McPherson, and Scott Burger, MD
Journal of Immunology. 2014 May; 192:69.15.

 

Cellular Raw Material Collection in Cell Therapy: Critical Determinant of Product Quality
Scott R. Burger, MD, Louis Juliano, and Wenshi Wang, PhD
Drug Discovery World. 2014; Volume I5, Issue 3 – Summer 20I4:29-34.
This article is summarized on HemaCare’s blog