Leukopaks from mobilized peripheral blood are collected from healthy human donors under IRB approved informed consent by leukapheresis using theSpectra Optia® Apheresis System CMNC collection protocol.Donors are injected with G-CSF, which stimulates the bone marrow to produce a large number of hematopoietic and progenitor stem cells and mobilizes them into the peripheral blood stream. This mononuclear cell-rich leukapheresis product is extracted using continuous flow centrifugal technology directly into the collection bag.
Fresh mobilized leukopaks must be used immediately upon receipt.
Testing: Donors are tested for HBV, HCV, HIV, HTLV, WNV, Trypanasoma cruzi, and Syphilis.
Mobilized Leukopak Flow Data
Representative flow data: Flow data on Certificate of Analysis for fresh mobilized leukopaks available upon request.