What Is Cord Blood?
Cord blood is the blood in the umbilical cord and placenta that is collected after the cord is cut immediately after birth. Postpartum collection of this material poses no risk to the mother or infant as this material is often discarded. However, parents may opt to store the umbilical cord blood for future therapeutic use with their children or they can donate the cord blood to advance science. Umbilical cord blood CD34+ cells are known to be a rich source of hematopoietic stem and progenitor cells, and are easily isolated using positive immunomagnetic cell separation procedures from umbilical cord blood.
Why Use Cord Blood Products?
Cord blood stem cells can differentiate into multiple cell types, making them popular across the research and development spectrum. Umbilical cord stem cells are being widely used in research, for example, to study normal human development, in drug discovery, for cell replacement, and cell repair. Cord blood and cells isolated from cord blood, such as CD34+ progenitor cells, are used in studies investigating cancers, anemias, immune system problems, brain and spinal cord injuries, to name a few. Because cord blood CD34+ cells are more naive than hematopoietic stem cells from other tissues, they are ideal for studies relating to transplantation and can be a great tool to bypass HLA mismatch issues.
How Are Cord Blood Products Collected?
Cord blood is collected aseptically at the time of delivery from IRB-consented healthy pregnant women. To collect cord blood, the clinician uses a needle to draw out the blood from the severed umbilical cord vein. The cord blood is then collected into a sterile bag containing anticoagulant.
Cord blood is shipped immediately to customers or processed following collection utilizing best-in-class instruments and media and standardized protocols. Rigorous operational controls ensure customers receive reproducible and consistent high-quality cells, eliminating variability. All isolated primary cells are characterized by flow cytometry prior to cryopreservation, guaranteeing customers receive a pure and viable cell population every time.